Celebrex and Gout Pains
Monday, October 19th, 2009
What is Celebrex and how can it help Gout pains?
Remedies have already existed even before modern medicine yet people control symptoms of gout through prescription medication. One of these medications is Celebrex.
Celebrex is used in treating joint pains particularly arthritis, menstrual cramps, ankylosing spondylitis and colonic polyps. Even though it is intended for pain relief, it does not get rid of the cause of gout which is the uric acid waste.
Pfizer exclusively sells the brand name Celebrex, while its generic name is Celecoxib but this is not available in US. Originally intended to provide pain relief, it tries to serve as an alternative to conventional NSAIDs while minimizing the latter’s adverse gastrointestinal effects. In reality, Celebrex is for patients who need regular and long-term pain relief.
Celecoxib or Celebrex is a COX-2 inhibitor. It blocks enzymes, therefore lowering concentrations of prostaglandins or cyclooxygenase 2— enzymes associated with pain. This reduce pain and inflammation brought about by osteoarthritis and rheumatoid arthritis. It likewise is used to combat gout pain.
Osteoarthritis is due to cartilage breakdown resulting in pain and stiffness. Rheumatoid arthritis, on the other hand, is more common in women than in men. It causes joint lining inflammation, resulting in swelling, stiffness, and redness.Because of the hindrance in enzymes, Celebrex helps reduce the common manifestations of inflammation, swelling, and tenderness associated with gout as well. Celebrex is a widely known now in gout pain management.
Celebrex was approved by the FDA in the U.S. in 1998. This was supported by a 12-month clinical trial involving 8, 059 patients by the manufacturing Searle division of Pfizer Pharmaceuticals.
Back in the early 1990s, the discovery of the -1 and -2 forms of cyclooxygenase led Pfizer to create Celebrex as a substitute pain reliever. This drug has lesser gastrointestinal side effects frequently associated with other NSAIDs like ibuprofen or naproxen.
In the next post, we will deal with the side effects of Celebrex and how a gout diet can be a better alternative to conventional NSAIDs for long term gout pain management.
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